Science & Health

CSIRO And Dell Develop Technology To Combat Post-Birth Complication

The CSIRO has teamed up with Dell to deliver CSIRO’s newest high performance computing cluster (HPC), named Pearcey. The Pearcey cluster supports CSIRO research activities in a broad range of areas such as Bioinformatics, Fluid Dynamics and Materials Science.

One CSIRO researcher is using Pearcey for the modelling work behind the development of an improved nylon mesh for use in pelvic organ prolapse (POP) surgery, which has the potential to benefit the one in five Australian women that have surgery for the condition at some point in their lives.

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Dr. Dayalan Gunasegaram, a CSIRO computational modeler, is that researcher. “Current mesh implants that haven’t been well designed for this purpose can lead to pain and discomfort, so we’ve teamed up with researchers from Monash University to develop an improved mesh for supporting prolapsed organs and treating the condition more effectively,” he said.

“Using the high performance computing capability of the Pearcey cluster we can simulate the stressful forces a patient would experience, such as during coughing or running, and model a variety of different situations to assess the mesh under stress.”

The new leading-edge computing hardware has helped to accelerate the research which would have taken longer without the specialised Pearcey cluster.

“With thousands of processor cores available, Pearcey allows us to do more finite element analysis computations within a given time, which means we’re able to advance to the next stage of testing much sooner than if we didn’t have something so powerful.

“The computer simulations allow us to better understand the cause-and-effect relationships between mesh parameters, such as pore size and their expected in-vivo performance after implantation, and really focus on the areas with the most influence.

“By focusing on these areas, we’re able to reduce the amount of physical testing we need to carry out on animals and humans, and the associated ethical and financial costs,” Dr. Gunasegaram continued.

The HPC cluster is named after Australian ICT pioneer Dr. Trevor Pearcey, who led the CSIRO project team that built one of the world’s first digital computers, CSIR Mk1 / CSIRAC.

Pearcey is a Dell HPC system designed by CSIRO and Dell that delivers 230 nodes supporting data-intensive research and computational modelling. It is based on Dell PowerEdge 13th generation M630 blade servers, each with 128GB RAM, and four PowerEdge R930 nodes each with 3 TB of memory for large memory applications.

Servers are connected via 1:1 Mellanox FDR InfiniBand Networking, and they are built with Bright Cluster Manager, enabling a software defined approach to management.

Sixteen of the PowerEdge M630 blade servers are configured with 512GB RAM and use ScaleMP software connected architecture to create a single, high memory, 8 TB cluster under a single operating system.

The manager for Dell APJ High-Performance Computing, Andrew Underwood, said “It’s vitally important we work closely with our customers to make sure we architect the right solution for their needs, and Pearcey is the result of more than three years of close collaboration with CSIRO’s Information Management and Technology team to clarify their objectives, and consolidate their infrastructure.”

“High performance computing facilities such as Pearcey are an integral part of the advanced information and communications technologies that enable CSIRO science to solve real issues.” said Angus Macoustra, executive manager of Scientific Computing at CSIRO.

“Pearcey joins our portfolio of scientific computing facilities – these world class computing and storage services are essential to the delivery of CSIRO’s research portfolio and allow us to accelerate research impact, and delivery to CSIRO’s customers compared to past systems.”

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