"Real-life" doesn't necessarily mean "true", especially when the context is ghost stories, but spooky legends have a way of influencing pop culture, as in the upcoming Winchester starring Helen Mirren. The film is based on the life of a real person who believed spirits were guiding the construction of her mansion.
Tagged With the amityville horror
There are two decent Amityville Horror movies: the 1979 original starring Margot Kidder and James Brolin, released when some still believed the book it was based on was a true story; and 2016's The Conjuring 2, which features a big scene in the infamous eye-window house, and is technically not part of the 18-film series anyway. Based on the below clip, it's safe to assume that Amityville: The Awakening will not do anything to save the series.