Video: Hey. Wanna see something so embarrassing for everyone involved that will make you break out in hives? Image: Star Trek: Voyager, "Deadlock" via Trek Core
In 1996, Star Trek turned 30 and had the requisite birthday party where the subject tries desperately to recapture the fun of his or her 20s. Unfortunately, Paramount and CBS decided to do that with the special Star Trek: 30 Years and Beyond. And so, the cast of Frasier (minus Frasier) joined Voyager (minus the crew, save a game Kate Mulgrew) for a sketch with the literal premise of "Frasier, but in space!"
If you look into Mulgrew's eyes at the end, you can see her crying for help.