Is High Fructose Corn Syrup Really So Evil?

Is High Fructose Corn Syrup Really So Evil?
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High fructose corn syrup seems to be in every freaking thing you buy at the supermarket these days. That’s because humans love sweet, and it’s cheaper than sugar.

The healthy set is collectively freaking out over the evils of HFCS (what the cool kids call it). Because, the children! And also grown ups! And health. But is the frenzy justified? Is high fructose corn syrup really any worse for you than sugar?

You may be surprised, as I was, to know that the jury is still out. HFCS has been so thoroughly vilified that I assumed the FDA or NIH or someone had databases overflowing with proof that HFCS was terrible for you. Actually, no.

HFCS and sugar are actually pretty similar. Sucrose, aka regular sugar, is half fructose and half glucose. Pay attention because these ingredients all end in -ose. HFCS contains the same ingredients at slightly different ratios: approximately 55 per cent fructose (like the name says, it’s high in the stuff) and 45 per cent glucose.

The ingredients also come from different places. Sucrose exists naturally in sugar cane, sugar beets, sugar-maple sap, dates and honey. High fructose corn syrup comes from straight corn syrup, which, before it is processed, is 100 per cent glucose. To make the ingredient in your soda, an enzyme turns 92 per cent of that glucose into fructose. Then glucose is added back into the mix, and, voila! High fructose corn syrup. While the 55 per cent fructose 45 per cent glucose is pretty standard, studies measuring the stuff in sodas turned up fructose levels over 60 per cent.

Why does that ratio matter? Studies have shown that fructose can be hard on the body. A study published in the Journal of Clinical Investigation compared the effects of fructose-sweetened drinks with glucose-sweetened drinks over the course of 10 weeks in overweight and obese subjects. About 25 per cent of the energy requirements over that time period came from the drinks (read: soda). While study participants gained about the same amount of weight regardless of sweetener, the fructose group — but not the glucose group — saw increases in belly fat as well as a dulling of insulin sensitivity.

But both regular sugar and HFCS are at least 50 per cent fructose, and it’s not enough for a HFCS indictment. “It definitely hasn’t been proven that that is true,” says Kimber Stanhope, a molecular biologist at the University of California at Davis, and author of the above study. “There is no data at this point showing a difference between the two. There is no reason at this point to think high fructose corn syrup is a bigger problem than sucrose.”

A study out of Princeton found that rats consuming high fructose corn syrup gained more weight than those consuming table sugar. But studies in humans, Stanhope explains, have not backed up the animal evidence.

All of this hand-wringing about HFCS is overshadowing the real problem: The astronomical amount of sugar of all kinds we eat on a daily basis. Government dietary guidelines say added sugar can be 25 per cent of our daily caloric intake and we can still be healthy. But Stanhope’s research says that’s too much. Her most recent sugar study, published in the Journal of Clinical Endocrinology & Metabolism, found that consuming that volume of sweets increased LDL cholesterol, triglycerides and levels of apolipoprotein-B: three big risk factors for heart disease. And in previous studies, sucrose has been shown to bump up lipid levels and fat storage in the liver.

There was a big jump in obesity in the 1970s, right around the same time HFCS entered the food and beverage industry. That might seem pretty damning for HFCS. But it’s likely that this cheaper way to make sweets led to a jump in consumption of high sugar foods. It doesn’t necessarily mean HFCS itself is to blame. So maybe we need to stop yapping about HFSC and eat our darn vegetables, for crying out loud.

Rachel Swaby is a freelance writer living in San Francisco.

Image: Flickr/BetsyWeber