I like the design on Toshiba's new portable hard drives. It may not be revolutionary, but there's something about the black and red swirl on the 640GB version that makes me think of throat lozenges. Tasty throat lozenges.
There are three versions available, each with its own colour (320GB in vivid white, 500GB in liquid blue and the 640GB rocket red). They're all USB 2.0 powered, small enough to carry around and if you're running Windows, there's automatic system backup software (NTI Backup Now EZ) on the device out of the box.
The 320GB version costs $129, the 500GB costs $169 and the 640GB is $199.