
Strokes and Parkinson’s Disease can cause irreparable damage to your grey matter. However, one controversial experiment aims to replace the function of those damaged areas with neural microchips.
For the experiment, a microchip is implanted under the skin of the rat’s skull with electrodes running a centimetre into the rodent’s cerebellum. The chip receives an input signal from the brain stem, analyses it, then forwards the information on to the brain’s motor centres.
To test the chip’s effectiveness, the team used a method similar to that which Pavlov employed with dogs. The rats were trained to associate a certain sound with a light puff of air on their eyes, which caused them to blink. Eventually, the rats blinked at the sound ahead of the puff of air. In rat’s with a damaged cerebellum, on the other hand, this motor function is lost completely and cannot be relearned by training another part of the brain to take over.
As Professor Matti Mintz, a member of the team at Tel Aviv University, explained to the BBC, “Imagine there’s a small area in the brain that is malfunctioning, and imagine that we understand the architecture of this damaged area. So we try to replicate this part of the brain with electronics.”
A neural chip that mimics the cerebellum’s function has already shown some success. “We constructed a simulation that works in a similar way to the original biological system — and when we see some recovery of the lost movement, it is clear that it is coming from our synthetic device and not from any other area of the brain,” said Professor Mintz.
Animal rights groups are, of course, up in arms over the live-animal testing. “This type of research raises enormous ethical concerns, let alone the poor animals whose lives are wasted on dubious and ego-driven experiments,” says Jan Creamer, CEO of the UK-based National Anti-Vivisection Society. [BBC News]


















Eccentric
Wednesday, January 18, 2012 at 9:27 AMScientists have been using live rats in surgical experiments for ages! I for one like the idea that one day if I get the dreaded Parkinson’s, there just might be a way to fix it. I also like the idea of enhancing the brain with extra memory and a decent math calculator!
TSH
Wednesday, January 18, 2012 at 4:28 PMI agree with animal rights campaigners that we ought not treat animals with unnecessary cruelty, and that we should be mindful of the lives we extinguish in order to further our own knowledge.
We kill feed animals every day for meat; we kill various flying and crawling insects without remorse just because their species is capable of transmitting disease; we accidentally squish bugs against our windscreens and decimate field-rodent populations with combine harvesters.
Now, if only a bunch of rats escaped (with the help of a male and female mouse, of course)… :–P
ravennoir
Thursday, January 19, 2012 at 11:46 AMI know scientists who do (or have) used rats for experiments, all of them are trained to ensure the animals suffer the least amount as possible (and probably get treat better than alot of peoples pets). Alot of people will benefit from this sort of research, but I suppose the activists would like the research to be completed the same way the Nazis did during the war, for the same results